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Type 2 Diabetes and Brain Health: New Research Insights on Dementia Risk
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Type 2 Diabetes and Brain Health: New Research Insights on Dementia Risk

Recent studies have shed new light on the relationship between type 2 diabetes and brain health issues such as dementia, as well as how lifestyle choices can influence these risks. The findings underscore the importance of maintaining stable blood sugar levels and adopting a healthy lifestyle to mitigate cognitive decline associated with diabetes.

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Study Shows How Night Shift Work Can Raise Risk of Diabetes, Obesity
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Study Shows How Night Shift Work Can Raise Risk of Diabetes, Obesity

Just a few days on a night shift schedule throws off protein rhythms related to blood glucose regulation, energy metabolism and inflammation, processes that can influence the development of chronic metabolic conditions. The finding, from a study led by scientists at Washington State University and the Pacific Northwest National Laboratory, provides new clues as to why night shift workers are more prone to diabetes, obesity and other metabolic disorders.

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Should Doctors Screen All Kids for Type 1 Diabetes?
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Should Doctors Screen All Kids for Type 1 Diabetes?

Millions worldwide live with type 1 diabetes, and for most the diagnosis came as a shock, following mysterious symptoms such as thirst and weight loss. But diabetes specialists have long known that certain blood tests can foretell the disease years earlier. That has left the field wrestling with a difficult question: Should healthy children get these blood tests, and would knowing about incipient diabetes help them? Early studies suggest antibody testing can prevent complications and delay disease, but some worry about psychological toll.

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NYITCOM Physician: Diabetes Patients Should Heed FDA Warning
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NYITCOM Physician: Diabetes Patients Should Heed FDA Warning

In late February, the Food and Drug Administration (FDA) warned diabetes patients not to use smartwatches or smart rings to measure their blood glucose levels. Following the FDA’s alert, obesity medicine expert Eleanor Yusupov, D.O., assistant professor at the College of Osteopathic Medicine, shares valuable insight for these patients.

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‘Bionic Pancreas’ Tested in San Antonio Adapts to Type 1 Diabetes Patients’ Needs
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‘Bionic Pancreas’ Tested in San Antonio Adapts to Type 1 Diabetes Patients’ Needs

Fifteen-year-old Mia Campos is living with Type 1 diabetes and can now enjoy everyday activities without any limitations thanks to her new "bionic pancreas." Campos's new “bionic pancreas” is a wearable, electronic device that replaces the role of her pancreas and adapts to the needs of her endocrine system over time. The iLet Insulin system was developed by Massachusetts-based Beta Bionics and is one of many new advances in diabetes management technology which are improving ways to automate insulin delivery.

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Diabetes and Liver Cancer — Stanford Medicine Study Suggests New Screening Guidelines
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Diabetes and Liver Cancer — Stanford Medicine Study Suggests New Screening Guidelines

A Stanford Medicine study identifies an easily measured biophysical property that can identify Type 2 diabetics at increased risk for liver cancer who don’t meet current screening guidelines. Researchers at Stanford University have shown that another biophysical characteristic known as viscoelasticity — think of how stretching a ball of Silly Putty or a clump of bread dough is met at first with resistance, and then with release — is even more tightly correlated with liver cancer than stiffness, particularly in people with Type 2 diabetes.

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Virginia Tech Researchers Awarded Nearly $2 Million To Explore New Treatment for Type 2 Diabetes and Obesity
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Virginia Tech Researchers Awarded Nearly $2 Million To Explore New Treatment for Type 2 Diabetes and Obesity

A team of Virginia Tech researchers was awarded nearly $2 million from the National Institute of Diabetes and Digestive and Kidney Disease, part of the National Institutes of Health, to explore novel approaches for treating Type 2 diabetes and obesity. The team of researchers, led by principal investigator Dongmin Liu, will study the impact of a derivative of secoiridoid, a natural compound found in certain plants like olives, on blood sugar control and obesity, which are often precursors to Type 2 diabetes.

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Transforming Diabetes Care with Precision Medicine
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Transforming Diabetes Care with Precision Medicine

“Precision medicine” involves customizing interventions to the unique genetic and molecular makeup of individual patients rather than relying on symptoms or broad categories. This approach, long associated with cancer treatment, is becoming increasingly critical for diabetes prevention and care. Precise diagnosis and disease characterization affect not only treatment choices but life planning, other health considerations, and even family members’ well-being. It means providing the right diagnosis, best care and insights into outcomes for all people with diabetes.

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Repurposed Drug Offers New Potential for Managing Type 1 Diabetes
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Repurposed Drug Offers New Potential for Managing Type 1 Diabetes

A recent study led by Indiana University School of Medicine in collaboration with the University of Chicago Medicine presents exciting future possibilities for the management of type 1 diabetes and the potential reduction of insulin dependency. The researchers’ findings, published in Cell Reports Medicine, suggest repurposing of the drug α-difluoromethylornithine (DFMO) may open doors to innovative therapies in the future.

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What Is Insulin Resistance and How Do You Know if You Have It?
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What Is Insulin Resistance and How Do You Know if You Have It?

According to the Centers for Disease Control and Prevention, 37.3 million adults have diabetes and 96 million — or more than one-third of Americans — have pre-diabetes. Because insulin resistance is a precursor to both, researchers estimate the number of people with insulin resistance is much higher.. “Most people don’t even know that they have it,” said Dr. Mary Vouyiouklis Kellis, an endocrinologist at Cleveland Clinic.

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Proteins Predict Significant Step Toward Development of Diabetes
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Proteins Predict Significant Step Toward Development of Diabetes

Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear. In a paper published online on June 29 in Cell Reports Medicine, researchers at the Department of Energy’s Pacific Northwest National Laboratory and their colleagues identify a set of altered proteins that predict a condition known as islet autoimmunity, a precursor for everyone who will ultimately develop Type 1 diabetes.

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Scientists Target Human Stomach Cells for Diabetes Therapy
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Scientists Target Human Stomach Cells for Diabetes Therapy

Stem cells from the human stomach can be converted into cells that secrete insulin in response to rising blood sugar levels, offering a promising approach to treating diabetes, according to a preclinical study from researchers at Weill Cornell Medicine.

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Too Much Insulin Can Be As Dangerous As Too Little
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Too Much Insulin Can Be As Dangerous As Too Little

One hundred years of research have greatly advanced medical and biochemical understanding of how insulin works and what happens when it is lacking, but the reverse, how potentially fatal insulin hyper-responsiveness is prevented, has remained a persistent mystery. In a new study, published in the April 20, 2023 online edition of Cell Metabolism, a team of scientists at the University of California San Diego School of Medicine, with colleagues elsewhere, describe a key player in the defense mechanism that safeguards us against excessive insulin in the body.

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Study Unlocks Potential Breakthrough In Type 1 Diabetes Treatment
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Study Unlocks Potential Breakthrough In Type 1 Diabetes Treatment

For the well over 700 million people around the globe living with type 1 diabetes, getting a host immune system to tolerate the presence of implanted insulin-secreting cells could be life-changing. Rice University bioengineer Omid Veiseh and collaborators identified new biomaterial formulations that could help turn the page on type 1 diabetes treatment, opening the door to a more sustainable, long-term, self-regulating way to handle the disease. To do so, they developed a new screening technique that involves tagging each biomaterial formulation in a library of hundreds with a unique “barcode” before implanting them in live subjects.

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